Ipamorelin is a synthetic pentapeptide and growth hormone secretagogue (GHS) that mimics ghrelin to selectively stimulate the pituitary gland to release growth hormone (GH) without significantly affecting cortisol or prolactin. Used in research, it promotes GH release for potential benefits in muscle growth, repair, anti-aging, and metabolic conditions, enhancing skin, hair, and nail health by boosting natural GH levels.
How it works
- Ghrelin Mimetic: Ipamorelin binds to ghrelin receptors (GHS-R1a) in the brain, tricking the pituitary into releasing GH.
- Selective Action: It’s known as a “selective” GHS because it primarily boosts GH, unlike older peptides that might raise other hormones like cortisol.
- Pulsatile Release: It encourages GH release in a natural, pulsatile pattern, similar to the body’s own production.
Potential benefits (Research/Anti-aging)
- Anti-aging: Promotes younger-looking skin, thicker hair, and stronger nails by increasing collagen and GH levels.
- Metabolic Health: May help with energy balance and metabolic conditions.
- Tissue Repair: Aids in wound healing and muscle recovery.
- Cognitive Function: Can improve mental clarity.
Usage & Form
- Form: Typically supplied as a sterile, freeze-dried powder, reconstituted with a bacteriostatic water.
- Storage: Stable for short periods at room temp but should be stored desiccated below -18°C (0°F) long-term.
Key Characteristics
- Peptide: A chain of 5 amino acids (Aib-His-D-2-Nal-D-Phe-Lys-NH₂).
- Research Tool: Primarily used in scientific study for its effects on GH release and related biological processes.
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