GHK-Cu (Glycyl-L-histidyl-L-lysine-Copper) is a naturally occurring peptide complex, essential for skin health, wound healing, and anti-aging, found in human plasma, saliva, and urine, but levels decline with age. This blue compound supports collagen production, acts as an antioxidant, reduces inflammation, stimulates blood vessel growth, and promotes tissue remodeling, making it popular in cosmetics for skin repair, firming, and hair growth, though much research is in early stages.
What it is
- A small peptide (Gly-His-Lys) that strongly binds to copper (Cu).
- Naturally present in the body, with levels decreasing significantly after age 20.
Key functions and benefits
- Skin & Wound Healing: Promotes collagen and glycosaminoglycan synthesis, improves wound contraction, and forms new tissue.
- Anti-Aging: Helps reverse age-related decline in tissue function, reduces inflammation, and offers antioxidant protection.
- Hair Growth: Rejuvenates hair follicles and supports scalp health.
- Gene Modulation: Can influence the expression of numerous human genes, including some overexpressed in cancer.
Uses
- Cosmetics: Widely used in serums and creams for anti-wrinkle, skin-firming, and anti-aging effects.
- Hair Products: Incorporated into treatments for thinning hair and alopecia.
- Research: Explored for broader applications in cognitive health, anti-inflammatory therapies, and tissue regeneration.





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