Cerebrolysin is a peptide-based drug derived from pig brain, used in many countries for neurological conditions like stroke, dementia (Alzheimer’s, vascular), and traumatic brain injury (TBI) to support brain self-repair and improve function. It contains neurotrophic factors, promotes neuroprotection, and is given as an injection or infusion, but while used widely, its benefits for stroke are debated, and side effects can include injection site reactions, nausea, headache, or dizziness.
What it is
- A mixture of low-molecular-weight peptides and amino acids from porcine (pig) brain.
- Contains growth factors like BDNF, NGF, and IGFs.
What it’s used for
- Stroke: To help recovery from acute ischemic stroke.
- Dementia: Vascular dementia, Alzheimer’s disease, and other forms.
- Traumatic Brain Injury (TBI): Post-surgery, concussion, and contusions.
- Cognitive Impairment: Memory and concentration disorders.
How it works
- Neuroprotection: Protects brain cells from damage.
- Neurotrophic effects: Supports nerve growth and repair.
- Neurorecovery: Enhances the brain’s ability to heal itself.
How it’s given
- Administered as an intramuscular (IM) or intravenous (IV) injection/infusion.
- Often given in cycles (e.g., 5 days a week for 4 weeks).
Potential side effects
- Injection site reactions (pain, redness).
- Nausea, headache, vertigo, dizziness, sleepiness.
Efficacy and usage
- Widely used in Eastern Europe, Asia, and Russia for various neurological conditions.
- Research continues, with some studies showing benefits for dementia and stroke recovery, while others note limited clear benefits for acute stroke and potential increased adverse events.
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