Sermorelin is a synthetic peptide that mimics natural growth hormone-releasing hormone (GHRH), stimulating the pituitary gland to release growth hormone (GH) for treating GH deficiency in children and sometimes adults, and for diagnostic testing, working by prompting the body’s own GH production, which can lead to improved growth, energy, and body composition, though potential side effects include injection site reactions, headaches, and dizziness, with rare risks of insulin resistance or heart issues with chronic, unregulated use.
How it Works
- Sermorelin is a fragment of human GHRH, a hormone that tells the pituitary gland to secrete GH.
- By stimulating GH release, it helps children grow and can improve body composition (muscle, fat) and energy in adults.
Uses
- Diagnosis: To assess growth hormone secretion and diagnose GH deficiency.
- Treatment: For children with growth failure due to insufficient GH.
- Off-label: Sometimes used for adults with GH deficiency or for anti-aging/wellness (though its FDA approval status varies).
Potential Benefits (with proper use)
- Increased energy, stamina, and focus.
- Improved muscle tone, strength, and skin quality.
- Weight loss, particularly abdominal fat.
- Enhanced sexual function and mood.
Common Side Effects
- Pain, redness, or swelling at the injection site.
- Mild headache, dizziness, or flushing.
- Nausea, fatigue, or itching.
Risks (especially with unregulated sources)
- Chronic GH excess can lead to insulin resistance, hypertension, or cardiac issues.
- Unregulated products may be contaminated or mislabeled, increasing risks.
Administration
- Typically administered via subcutaneous injection, often at bedtime.
- Requires prescription and medical supervision.
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