CJC-1295 without DAC (Modified GRF (1-29)) is a synthetic peptide that stimulates the pituitary gland to release growth hormone (GH) in natural, short pulses, mimicking the body’s own rhythms, unlike the DAC version which has a long-acting binding complex. It’s used for promoting muscle growth, fat loss, and recovery but requires frequent dosing (multiple times daily) due to its short half-life (around 30 mins-1 hour). It’s known for stimulating GH release without causing pituitary desensitization, making it popular for long-term use, often combined with Ipamorelin.

Key Characteristics

Action: Mimics GHRH (Growth Hormone-Releasing Hormone) to boost natural GH production.
No DAC: Lacks the Drug Affinity Complex, resulting in a short half-life.
Dosing: Needs frequent injections (multiple times daily) to maintain effect.
GH Release: Creates rapid, short, pulsatile GH spikes, similar to the body’s natural pattern.
Benefits: Muscle gain, fat loss, improved recovery, increased energy, supports natural hormone rhythms.

How it Differs from CJC-1295 with DAC

CJC-1295 (No DAC): Short half-life, frequent dosing, natural GH pulses, better for long-term use without desensitization.
CJC-1295 (with DAC): Extended half-life (days), less frequent dosing, sustained GH levels but can suppress natural pulsatility over time.

Common Uses & Combinations

Often used in combination with other peptides like Ipamorelin to synergistically increase GH release.
Aims to support increased lean mass, fat metabolism, and cellular repair.